Taurohyodeoxycholic acid sodium salt hydrate

Taurohyodeoxycholic acid sodium salt hydrate
  • CAS No.:38411-85-7
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Taurohyodeoxycholic acid sodium salt hydrate Basic information
Product Name:Taurohyodeoxycholic acid sodium salt hydrate
Synonyms:Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
CAS:38411-85-7
MF:C26H46NNaO6S
MW:523.7
EINECS:
Product Categories:
Mol File:38411-85-7.mol
Taurohyodeoxycholic acid sodium salt hydrate Chemical Properties
Safety Information
WGK Germany 3
MSDS Information
Taurohyodeoxycholic acid sodium salt hydrate Usage And Synthesis
DescriptionTaurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
UsesSodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.
General DescriptionSodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent.
Taurohyodeoxycholic acid sodium salt hydrate Preparation Products And Raw materials

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