7-Dehydrocholesterol-25,26,26,26,27,27,27-d7

CAS No.：388622-58-0

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Basic information

Product Name:	7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
Synonyms:	(32)-7-Dehydro Cholesterol-d7 (Major);7-dehydro Cholesterol-d7;7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;(3β)-7-Dehydro Cholesterol-d7 (Major);(3β)-7-Dehydro Cholesterol-d7 (See also D229462)
CAS:	388622-58-0
MF:	C27H44O
MW:	384.65
EINECS:
Product Categories:
Mol File:	388622-58-0.mol

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemical Properties

storage temp.	-70°C
form	solid

Safety Information

WGK Germany

MSDS Information

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Usage And Synthesis

Uses	7-dehydrocholesterol-d7 has been used: as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis
General Description	7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol.
Biochem/physiol Actions	7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS).

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Preparation Products And Raw materials

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873