1-(4-Methoxyphenyl)piperazine dihydrochloride

CAS No.：38869-47-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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1-(4-Methoxyphenyl)piperazine dihydrochloride Basic information

Product Name:	1-(4-Methoxyphenyl)piperazine dihydrochloride
Synonyms:	TIMTEC-BB SBB003069;N-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE;PMPP DIHYDROCHLORIDE;1-(P-METHOXYPHENYL)PIPERAZINE DI HCL;1-(4-METHOXYLPHENYL)-PIPERAZINE DIHYDROCHLORIDE;1-(4-METHOXYPHENYL) PIPERAZINE 2HCL;1-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE;1-(4-Methoxyphenyl)piperazine Dihydrochloride (discontinued see M266215)
CAS:	38869-47-5
MF:	C11H18Cl2N2O
MW:	265.18
EINECS:	254-166-6
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Piperidines, Piperidones, Piperazines;Pyrans, Piperidines & Piperazines;Building Blocks;Heterocyclic Building Blocks;Nitrogen cyclic compounds;Piperazines;Pyrans, Piperidines &Piperazines;Piperaizine;Piperazine derivates;API intermediates;Aromatics;Heteroctcles;Intermediates;Building Blocks;C11;Chemical Synthesis;Heterocyclic Building Blocks
Mol File:	38869-47-5.mol

1-(4-Methoxyphenyl)piperazine dihydrochloride Chemical Properties

Melting point	240 °C (dec.)(lit.)
storage temp.	-20°C Freezer
form	powder to crystal
color	White to Light yellow to Light red
Water Solubility	very faint turbidity
Sensitive	Hygroscopic
BRN	4275784
InChIKey	MMXANKLJIHSIQH-UHFFFAOYSA-N
CAS DataBase Reference	38869-47-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	28A-26-36-24/25
RIDADR	2811
WGK Germany	3
HazardClass	6.1
PackingGroup	III
HS Code	29349990

MSDS Information

Provider	Language
1-(4-Methoxyphenyl)piperazine dihydrochloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

1-(4-Methoxyphenyl)piperazine dihydrochloride Usage And Synthesis

Description	1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine. It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described. This product is intended for research and forensic purposes.
Chemical Properties	Off-White Powder
Uses	An intermediate in the synthesis of Itraconazole (I937500).
Uses	1-(4-Methoxyphenyl) piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine. It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described. This product is intended for research and forensic purposes.

1-(4-Methoxyphenyl)piperazine dihydrochloride Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Methanol-->Dichloromethane-->Sodium carbonate-->Magnesium sulfate-->p-Anisidine-->Bis(2-chloroethyl)amine hydrochloride-->Diethylene glycol monomethyl ether

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