Other grades of this product :
| Proteasome Inhibitor XVI Basic information |
| Product Name: | Proteasome Inhibitor XVI | | Synonyms: | Proteasome Inhibitor XVI;AdaAhxLVS - CAS 389064-25-9 - Calbiochem;L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]- | | CAS: | 389064-25-9 | | MF: | C50H88N6O8S | | MW: | 933.33 | | EINECS: | | Product Categories: | | Mol File: | 389064-25-9.mol |
| Proteasome Inhibitor XVI Chemical Properties |
| Boiling point | 1161.4±65.0 °C(Predicted) | | density | 1.096±0.06 g/cm3(Predicted) | | storage temp. | -20C | | form | Off-white powder | | pka | 13.41±0.46(Predicted) |
| Proteasome Inhibitor XVI Usage And Synthesis |
| General Description | A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM). | | Biochem/physiol Actions | Cell permeable: yes |
| Proteasome Inhibitor XVI Preparation Products And Raw materials |
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