Product

(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE

CAS No.：389130-06-7

Other grades of this product :

(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE Basic information

Reaction

Product Name:	(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE
Synonyms:	(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE;(S)-(+)-(8,9,10,11,12,13,14,15-Octahydro-3,5-dioxa-4-phosphacyclohepta[2.1-a.3.4-a']dinaphthalen-4-yl)dimethylamine;(S)-(+)-(8,9,10,11,12,13,14,15-Octahydro-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)dimethylamine,99%;(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1μ,2μ-f][1,3,2]dioxaphosphepin-4-amine;(S)-N,N-Dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho-[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4;(11bS)-8,9,10,11,12,13,14,15-octahydro-N,N-diMethyl-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-aMine;MonoPhos Ligand
CAS:	389130-06-7
MF:	C22H26NO2P
MW:	367.42
EINECS:
Product Categories:	Chiral Phosphine;CPN;Chiral Catalysts, Ligands, and Reagents;DSM MonoPhos Phosphoramidites;Privileged Ligands and Complexes
Mol File:	389130-06-7.mol

(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE Chemical Properties

Melting point	112-113°C
alpha	+318° (c 0.63, THF)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Powder
color	white
optical activity	[α]22/D 282.0°, c = 1 in chloroform
Sensitive	moisture sensitive, store cold
CAS DataBase Reference	389130-06-7

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36/37/39
WGK Germany	3

MSDS Information

(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE Usage And Synthesis

Reaction

A ligand for enantioselective hydrogenation of prochiral functional olefins.

Uses

(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine is a monodentate phosphoramidite (MonoPhos) chiral ligand that can be used:

In the Cu-catalyzed synthesis of chiral 3-(arylbut-1-yn-1-yl)silane derivatives by reacting N-tosylhydrazones with silyl-substituted alkynes via asymmetric insertion.
In the Rh-catalyzed asymmetric hydrogenation of R-isopropylcinnamic acid derivative, a key intermediate of renin inhibitor aliskiren.
In the Rh-catalyzed conjugate addition of arylboronic acids to lactones, enones, and nitroalkenes.

(S)-(+)-(8,9,10,11,12,13,14,15-OCTAHYDRO-3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)DIMETHYLAMINE Preparation Products And Raw materials

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873