4-Morpholinecarbonyl chloride

4-Morpholinecarbonyl chloride
  • CAS No.:15159-40-7
Other grades of this product :
4-Morpholinecarbonyl chloride Basic information
Product Name:4-Morpholinecarbonyl chloride
Synonyms:4-Chlorocarbonylmorpholine Morpholinocarbonyl Chloride;4-Morpholinecarbonyl;MORPHOLINE-4-CARBONYL CHLORIDE;MORPHOLIN-4-YLCARBONYL CHLORIDE;MORPHOLINOCARBONYL CHLORIDE;4-MORPHOLINE CARBONIC ACID CHLORIDE;4-MORPHOLINECARBONYL CHLORIDE;4-MORPHOLINYLCARBONYL CHLORIDE
CAS:15159-40-7
MF:C5H8ClNO2
MW:149.58
EINECS:239-213-0
Product Categories:Phosgene Derivatives;Building Blocks;Heterocyclic Building Blocks;Morpholines;Building Blocks;Chemical Synthesis;ACIDHALIDE;Heterocyclic Building Blocks;Morpholines/Thiomorpholines
Mol File:15159-40-7.mol
4-Morpholinecarbonyl chloride Chemical Properties
Boiling point 137-138 °C/33 mmHg (lit.)
density 1.282 g/mL at 25 °C (lit.)
refractive index n20/D 1.498(lit.)
Fp >230 °F
storage temp. Inert atmosphere,2-8°C
pka-2.16±0.20(Predicted)
form clear liquid
color Colorless to Light yellow
BRN 116257
CAS DataBase Reference15159-40-7(CAS DataBase Reference)
EPA Substance Registry System4-Morpholinecarbonyl chloride (15159-40-7)
Safety Information
Hazard Codes Xn
Risk Statements 14-36/38-40
Safety Statements 26-30-36-38
RIDADR UN 3265 8/PG 2
WGK Germany 3
10-21
HazardClass 8
PackingGroup II
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Morpholinecarbonyl chloride Usage And Synthesis
UsesPhotographic intermediate
Uses4-Morpholinecarbonyl chloride may be used in the preparation of a versatile fluorogenic label for biomolecular imaging. It may be used in the synthesis of:
  • morpholine-4-carboxylic acid [4-(2,4-dimethylphenyl)thiazol-2-yl]amide
  • morpholine-4-carboxylic acid [4-(2,4,6-trimethylphenyl)thiazol-2-yl]amide
  • 2-isopropyl-6-methylpyrimidin-4-yl morpholine-4-carboxylate
General Description4-Morpholinecarbonyl chloride is a photographic intermediate. Rates of solvolysis of 4-morpholinecarbonyl chloride with N-alkyl group in aqueous binary solvents of acetone, ethanol, methanol, methanol-d, 2,2,2-trifluoroethanol, pure water and D2O has been determined. Preparation of 4-morpholinecarbonyl chloride has been reported.

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