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| 2,2-DIFLUOROACETOPHENONE Basic information |
| Product Name: | 2,2-DIFLUOROACETOPHENONE | | Synonyms: | A,A-DIFLUOROACETOPHENONE;ALPHA,ALPHA-DIFLUOROACETOPHENONE;Ethanone, 2,2-difluoro-1-phenyl- (9CI);2,2-Difluoroacetophenone,95%;2,2-Difluoro-1-phenylethan-1-one;2,2-Difluoroacetophenone 97%;2,2-Difluoro-1-phenylethan-1-one, 2,2-Difluoro-1-phenyl-1-oxoethane;2,2-DIFLUOROACETOPHENONE | | CAS: | 395-01-7 | | MF: | C8H6F2O | | MW: | 156.13 | | EINECS: | | Product Categories: | ACETYLHALIDE | | Mol File: | 395-01-7.mol |
| 2,2-DIFLUOROACETOPHENONE Chemical Properties |
| Melting point | 48-50°C | | Boiling point | 53-54°C/12mm | | density | 1.180±0.06 g/mL | | refractive index | 1.4955 | | Fp | 53-54°C/12mm | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | liquid | | Water Solubility | Immiscible with water. | | CAS DataBase Reference | 395-01-7 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 2914790090 |
| 2,2-DIFLUOROACETOPHENONE Usage And Synthesis |
| Uses | 2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee. | | Synthesis Reference(s) | Tetrahedron, 52, p. 15, 1996 DOI: 10.1016/0040-4020(95)00884-B |
| 2,2-DIFLUOROACETOPHENONE Preparation Products And Raw materials |
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