2-Nitrobenzyl bromide

2-Nitrobenzyl bromide
  • CAS No.:3958-60-9
Other grades of this product :
2-Nitrobenzyl bromide Basic information
Product Name:2-Nitrobenzyl bromide
Synonyms:1-(Bromomethyl)-2-nitrobenzene;1-Bromomethyl-2-nitro-benzene;Benzene, 1-(bromomethyl)-2-nitro-;-Bromo-2-mitrotoluene;o-Nitrobenaylbromide;2-NITROBENZYL BROMIDE;2-(BROMOMETHYL)NITROBENZENE;A-BROMO-O-NITROTOLUENE
CAS:3958-60-9
MF:C7H6BrNO2
MW:216.03
EINECS:223-558-9
Product Categories:Biochemistry;Nucleosides, Nucleotides & Related Reagents;Aromatic Halides (substituted);Protecting Agents for Hydroxyl and Amino Groups;Protecting Agents, Phosphorylating Agents & Condensing Agents
Mol File:3958-60-9.mol
2-Nitrobenzyl bromide Chemical Properties
Melting point 44-46 °C (lit.)
Boiling point 265.51°C (rough estimate)
density 1.6841 (rough estimate)
refractive index 1.6120 (estimate)
Fp >230 °F
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form Crystals or Crystalline Powder
color Yellow to light brown
Water Solubility insoluble
BRN 638991
CAS DataBase Reference3958-60-9(CAS DataBase Reference)
NIST Chemistry Reference2-Nitrobenzyl bromide(3958-60-9)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR UN 3261 8/PG 2
WGK Germany 3
4.8-19-21
HazardClass 8
PackingGroup II
HS Code 29049085
MSDS Information
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2-Nitrobenzyl bromide English
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2-Nitrobenzyl bromide Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
Uses2-Nitrobenzyl bromide is used in the preparation of S-2-nitrobenzyl-cysteine by reaction with L-cysteine. It is also used for the introduction of the 2-nitrobenzyl protecting group in organic synthesis. It plays an important role in the production of expectorant agent. Further, it is employed for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. In addition to this, it is used in the preparation of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.
Uses2-Nitrobenzyl bromide was used for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. It can be used in the synthesis of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.
Biochem/physiol Actions2-Nitrobenzyl bromide reacts with L-cysteine to form S-2-nitrobenzyl-cysteine which was used for modification of ultra-low-gelling-temperature (ULGT) agarose.

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