2-(METHYLSULFONYL)ETHANOL

CAS No.：15205-66-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-(METHYLSULFONYL)ETHANOL Basic information

Product Name:	2-(METHYLSULFONYL)ETHANOL
Synonyms:	2-(Methylsulfonyl)ethanol,2-Hydroxyethyl methyl sulfone;2-(Methylsulfonyl)ethanol, 98% 10GR;4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)-4-oxobutanoic acid;Ethanol, 2-(methylsulfonyl)-;hydroxyethyl;hydroxyethylmethylsulfone;2-(METHYLSULFONYL)ETHANOL;2-(METHANESULFONYL)ETHANOL
CAS:	15205-66-0
MF:	C3H8O3S
MW:	124.16
EINECS:	239-261-2
Product Categories:	Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfones;Sulfur Compounds;INDOLE
Mol File:	15205-66-0.mol

2-(METHYLSULFONYL)ETHANOL Chemical Properties

Melting point	31-33 °C(lit.)
Boiling point	148-149 °C(lit.)
density	1.33
refractive index	1.478-1.48
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	solid
pka	13.61±0.10(Predicted)
color	White to Almost white
Water Solubility	Soluble in water.
BRN	1746915
CAS DataBase Reference	15205-66-0(CAS DataBase Reference)

Safety Information

Safety Statements	22-24/25
WGK Germany	3
F	3-9
HS Code	29309090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

2-(METHYLSULFONYL)ETHANOL Usage And Synthesis

Chemical Properties	Clear yellow liquid or low melting solid
Uses	2-(Methylsulfonyl)ethanol may be used as reagent in the synthesis of phenols from aryl fluorides. It may be used in the preparation of 2-(methylsulfonyl)ethyl N,N-bis(2-chloroethyl)phosphorodiamidate. 2-Hydroxyethyl Methyl Sulfone, is the versatile building block used in the synthesis of more complex sulfur containing compounds. It can be used for the studies of inhibitor and substrate moieties to acetylcholinesterase.
General Description	Reaction of 2-(methylsulfonyl)ethanol with cotton cellulose yields methylsulfonylethyl substituents in the 2-O- to 6-O-positions of the monosubstituted D-glucopyranosyl unit of cotton cellulose.

2-(METHYLSULFONYL)ETHANOL Preparation Products And Raw materials

Raw materials	Ethanol, 2-(methylsulfonyl)-, 1-acetate-->2-(METHYLTHIO)ETHANOL-->ETHYLENE OXIDE-->Methanesulfonyl chloride-->Acetic acid
Preparation Products	2-(methylsulfonyl)ethyl methanesulfonate-->Methyl vinyl sulfone-->Hydrochloric acid

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