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| 1-(2-Furoyl)piperazine Basic information |
| 1-(2-Furoyl)piperazine Chemical Properties |
| Melting point | 67-70 °C(lit.) | | Boiling point | 137-140°C 0,1mm | | density | 1.1819 (rough estimate) | | refractive index | 1.5373 (estimate) | | Fp | >230 °F | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform, Methanol (Slightly) | | form | neat | | pka | 8.37±0.10(Predicted) | | color | White to Pale Yellow | | Sensitive | Hygroscopic | | BRN | 880196 | | Stability: | Very Hygroscopic | | CAS DataBase Reference | 40172-95-0(CAS DataBase Reference) |
| 1-(2-Furoyl)piperazine Usage And Synthesis |
| Chemical Properties | white to light yellow solid | | Uses | 2-Furanyl-1-piperazinylmethanone was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase. | | Uses | 2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase. | | Uses | 1-(2-Furoyl)piperazine may be used to synthesize: - 2-[4-(2-furoyl) piperazin-1-yl]-4-amino-6-benzyloxy-7-methoxyquinazoline hydrochloride monohydrate
- 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-7-benzyloxy-6-methoxyquinazoline hydrochloride monohydrate
- 4-amino-2-[4-(2-furoyl)piperazin-1-yl]-quinazoline hydrochloride
- 6,7-dimethoxy-2-[4-(2-furoyl)-piperazin-1-yl]quinazoline-4-one hydrate
- 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-furoyl)-piperazine hydrogen oxalate
- 1-(3,4-dichlorobenzyl)-4-(2-furoyl)-piperazine hydrogen oxalate
- 4-(9-fluorenyl)-1-(2-furoyl)piperazine
- 2-[4-(2-furoyl)piperazin-1-yl]-benzimidazole hydrochloride hydrate
| | Synthesis Reference(s) | Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031 |
| 1-(2-Furoyl)piperazine Preparation Products And Raw materials |
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