Other grades of this product :
| Product Name: | DMEOB | | Synonyms: | DMEOB;[(3-METHOXYPHENYL)METHYLENE]HYDRAZONE-3-METHOXYBENZALDEHYDE;3-METHOXYBENZALDEHYDE [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE;bis(3-methoxybenzylidene)hydrazine;Benzaldehyde, 3-methoxy-, 2-[(3-methoxyphenyl)methylene]hydrazone | | CAS: | 40252-74-2 | | MF: | C16H16N2O2 | | MW: | 268.31 | | EINECS: | | Product Categories: | Glutamate receptor | | Mol File: | 40252-74-2.mol |
| DMEOB Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: insoluble | | form | solid | | color | yellow |
| DMEOB Usage And Synthesis |
| Uses | DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s. | | Biological Activity | Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M). | | Biochem/physiol Actions | Negative allosteric modulator at the metabotropic glutamate receptor mGluR5. |
| DMEOB Preparation Products And Raw materials |
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