2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE

CAS No.：41351-30-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE Basic information

Product Name:	2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
Synonyms:	RINK ACID REAGENT;RINK KETONE LINKER;2,4-DIMETHOY-4'-HYDROXYBENZOPHENONE;(2,4-DIMETHOXYPHENYL)-(4-HYDROXYPHENYL)METHANONE;2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE;AKOS BC-0909;4'-HYDROXY-2,4-DIMETHOXYBENZOPHENONE;DMHB
CAS:	41351-30-8
MF:	C15H14O4
MW:	258.27
EINECS:
Product Categories:	Bifunctional Crosslinkers;Building Blocks;C15 to C38;Carbonyl Compounds;Chemical Biology;Chemical Synthesis;Aromatic Benzophenones & Derivatives (substituted);Combinatorial Chemistry;Linkers;Synthetic Organic Chemistry;Ketones;Organic Building Blocks;Peptide Chemistry
Mol File:	41351-30-8.mol

2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE Chemical Properties

Melting point	138-142 °C (lit.)
Boiling point	467.9±45.0 °C(Predicted)
density	1.206±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	soluble in Methanol
pka	7.73±0.15(Predicted)
form	Powder
color	Off-white to white
BRN	2508320
CAS DataBase Reference	41351-30-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
Hazard Note	Irritant
HS Code	29145090

MSDS Information

Provider	Language
SigmaAldrich	English

2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE Usage And Synthesis

Chemical Properties	2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is white to off-white powder
Uses	2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used for solid-phase peptide synthesis with FMOC strategy
Preparation	Preparation by Friedel–Crafts acylation of resorcinol dimethyl ether with p-hydroxybenzoic acid, ? in the presence of zinc chloride and phosphorous oxychloride at 60–65° for 1.5 h (71%) or in nitrobenzene at 60° for 2–3 h; ? in the presence of polyphosphoric acid.

2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE Preparation Products And Raw materials

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