(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-

(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
  • CAS No.:42203-78-1
Other grades of this product :
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Basic information
Product Name:(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
Synonyms:(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-;4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride;Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride;Doi cpd hydrochloride;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride;BenzeneethanaMine,4-iodo-2,5-diMethoxy-a-Methyl-, hydrochloride (1:1);(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution;DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
CAS:42203-78-1
MF:C11H16INO2.ClH
MW:357.613
EINECS:636-989-6
Product Categories:
Mol File:42203-78-1.mol
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Chemical Properties
Fp 9℃
storage temp. Store at RT
solubility H2O: soluble10mg/mL
form solid
color white to off-white
Safety Information
Hazard Codes Xi,T,F
Risk Statements 36/37/38-39/23/24/25-23/24/25-11
Safety Statements 22-26-36-45-36/37-16-7
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
MSDS Information
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Usage And Synthesis
General DescriptionA Certified Spiking Solution? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action.
Biological ActivityBrain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α .
Biochem/physiol Actions(±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum.
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Preparation Products And Raw materials

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