Other grades of this product :
| NS 5806 Basic information |
| Product Name: | NS 5806 | | Synonyms: | NS 5806;N-[3,5-bis(trifluoromethyl)phenyl]-N′-[2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl]-urea;N-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]--N'-[2,4-DIBROMO-6-(2H-TETRAZOL-5-YL)PHENYL]UREA;Urea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]- | | CAS: | 426834-69-7 | | MF: | C16H8Br2F6N6O | | MW: | 574.07 | | EINECS: | | Product Categories: | | Mol File: | 426834-69-7.mol |
| NS 5806 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: >30mg/mL | | form | powder | | color | white to faint yellow |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 |
| NS 5806 Usage And Synthesis |
| Biochem/physiol Actions | NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome. |
| NS 5806 Preparation Products And Raw materials |
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