| ZOPICLONE N-OXIDE Basic information |
| Product Name: | ZOPICLONE N-OXIDE |
| Synonyms: | RP 2975;1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester;Zopiclone N-Oxide(Mixture of diastereomers);RP 29753;Zopiclone N-Oxide (Eszopiclone Impurity A)(Mixture of Diastereomers);Zopiclone N-Oxide (Eszopiclone Impurity A) ;ZOPICLONE N-OXIDE;4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester 4-oxide |
| CAS: | 43200-96-0 |
| MF: | C17H17ClN6O4 |
| MW: | 404.81 |
| EINECS: | 641-896-9 |
| Product Categories: | Isotopically Labeled Pharmaceutical Reference Standard;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Impurities |
| Mol File: | 43200-96-0.mol |
| ZOPICLONE N-OXIDE Chemical Properties |
| Melting point | >140°C (dec.) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Soni |
| form | neat |
| pka | 4.92±0.20(Predicted) |
| color | White to Light Brown |
| Safety Information |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol |
| WGK Germany | 1 |
| HS Code | 2933790002 |
| MSDS Information |
| ZOPICLONE N-OXIDE Usage And Synthesis |
| Chemical Properties | Off-White to Pale Beige Solid |
| Uses | A metabolite of Zopiclone |
| Uses | Eszopiclone impurity A. |
| General Description | Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane?and ZImovane?and is used in the treatment of insomnia. |
| ZOPICLONE N-OXIDE Preparation Products And Raw materials |
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