COENZYME Q4

COENZYME Q4
  • CAS No.:4370-62-1
Other grades of this product :
COENZYME Q4 Basic information
Product Name:COENZYME Q4
Synonyms:COENZYME Q4;2,3-DIMETHOXY-5-METHYL-6-(GERANYLGERANYL)-1,4-BENZOQUINONE;Q-4;UBIQUINONE-20;UBIQUINONE-4;2,3-dimethoxy-5-methyl-6-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]cyclohexa-2,5-diene-1,4-dione;Ubiquinone Q4;2,3-Dimethoxy-5-methyl-6-(geranylgeranyl)-1,4-benzoquinone, Q-4, Ubiquinone-20, Ubiquinone-4
CAS:4370-62-1
MF:C29H42O4
MW:454.64
EINECS:215-668-0
Product Categories:
Mol File:4370-62-1.mol
COENZYME Q4 Chemical Properties
storage temp. -20°C
BRN 2066531
Safety Information
Safety Statements 22-24/25
WGK Germany 3
8-10
MSDS Information
ProviderLanguage
SigmaAldrich English
COENZYME Q4 Usage And Synthesis
UsesCoenzyme Q4 (CoQ4) is a 4 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ4 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution.
Biochem/physiol ActionsIncreases the fluorescence polarization of perylene incorporated into ubiquinone-depleted mitochondrial and bilayer vesicles prepared from mitochondrial phospholipids
Purification MethodsIt is a redoil which can be purified by chromatography on SiO2 plates and eluted with Et2O/hexane. The purity is checked by HPLC (silica column using 7% Et2O/hexane). It has max 270 nm ( 14,800) in pet ether. [NMR and MS: Naruta J Org Chem 45 4097 1980, cf Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491]. It has also been dissolved in MeOH/EtOH (1:1 v/v) and kept at 5o until crystals appear [Lester & Crane Biochim Biophys Acta 32 497 1958].
COENZYME Q4 Preparation Products And Raw materials

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