(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

CAS No.：442905-33-1

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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Basic information

Reactions

Product Name:	(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
Synonyms:	CTH-(R)-XYLYL-P-PHOS;CTH-(S)-XYLYL-P-PHOS;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE;(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE;(R)-XYLYL-P-PHOS;(S)-XYLYL-P-PHOS;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&;min.cth-(r)-xylyl-p-phos
CAS:	442905-33-1
MF:	C46H50N2O4P2
MW:	756.85
EINECS:
Product Categories:
Mol File:	442905-33-1.mol

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties

Melting point	190-194°C
Boiling point	791.1±60.0 °C(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	-1.76±0.38(Predicted)
form	Powder
color	white to pale yellow
optical activity	[α]20/D +125°, c = 1 in chloroform
Water Solubility	Sparingly soluble in water.

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39-36
WGK Germany	3

MSDS Information

Provider	Language
ALFA	English

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Usage And Synthesis

Reactions	Chiral ligand for ruthenium- catalyzed asymmetric hydrogenation of aromatic ketones. Chiral ligand for iridium-catalyzed asymmetric hydrogenation of quinolines. Chiral ligand for copper- catalyzed asymmetric hydrosilylation of ketones. Synthesis of new chiral 2-functionized-1,2,3,4-tetrahydroquinoline derivatives via asymmetric hydrogenation of substituted quinolines. Rhodium-biphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.
Chemical Properties	White solid
Uses	(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in asymmetric hydrogenation.It acts as a ligand used in the asymmetic hydrogenation of β-keto esters, 2-arylacrylates, aryl ketones , and other substrates. Other applications include it is used widely as a Catalyst, when combined with Rh, Ru and Ir precursor.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Preparation Products And Raw materials

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