4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
  • CAS No.:457961-34-1
Other grades of this product :
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Basic information
Product Name:4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
Synonyms:1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine;4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole;1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine;AA92593;Cy1001;Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-;AA92593 >=98% (HPLC)
CAS:457961-34-1
MF:C13H19NO3S
MW:269.36
EINECS:
Product Categories:
Mol File:457961-34-1.mol
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Chemical Properties
storage temp. -20°C
solubility DMSO: soluble10mg/mL, clear
form powder
color white to beige
Safety Information
Hazard Codes Xi
Risk Statements 36-37-38
Safety Statements 26
WGK Germany 3
HS Code 2933998090
MSDS Information
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Usage And Synthesis
UsesAA92593 has been used as a selective melanopsin inhibitor.
Biochem/physiol ActionsAA92593 is an opsinamide, a potent antagonist of melanopsin-mediated phototransduction with an IC50 of 665 nM in a Ca2+ flux assay in CHO cells expressing melanopsin (Opn4) and selectivity > 10 μM at 74 common biological targets. AA41612 is believed to act by competing for binding to melanopsin. AA41612 inhibited mouse pupillary light reflex and light aversion in vivo. AA92593 and similar compounds might be useful in alleviating the photophobia associated with migraine.
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Preparation Products And Raw materials

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