(R)-(-)-Phenylsuccinic acid
(R)-(-)-Phenylsuccinic acid
  • CAS No.:46292-93-7
Other grades of this product :
(R)-(-)-Phenylsuccinic acid Basic information
Product Name:(R)-(-)-Phenylsuccinic acid
Synonyms:(R)2-Phenylsuccinicacid;(R)-(-)-PHENYLSUCCINIC ACID;(R)-(-)-PHENYLSUCCINIC ACID 99+%;(R)-2-Phenylbutanedioic acid;Butanedioic acid, 2-phenyl-, (2R)-;(R)-(-)-Phenylsuccinic acid >=96.0% (sum of enantiomers, HPLC);(2R)-2-Phenylbutanedioic acid;(2R)-2-Phenylbutanedioicacid>99%ee
CAS:46292-93-7
MF:C10H10O4
MW:194.18
EINECS:
Product Categories:Miscellaneous;Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks
Mol File:46292-93-7.mol
(R)-(-)-Phenylsuccinic acid Chemical Properties
Melting point 173-176 °C
alpha -175 º (c=1%, acetone)
Boiling point 290.62°C (rough estimate)
density 1.2534 (rough estimate)
refractive index 1.5430 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Acetone (Slightly), Methanol (Slightly)
pka3.60±0.10(Predicted)
form Solid
color White to Off-White
optical activity[α]20/D 175±4°, c = 1% in acetone
BRN 3201702
CAS DataBase Reference46292-93-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2917399590
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(-)-Phenylsuccinic acid Usage And Synthesis
Chemical Propertiesalmost white fine powder
Uses(R)-Phenylsuccinic Acid is an intermediate used in the preparation of optically active succinic acid derivatives used as hypoglycemic agents.
Purification MethodsPurify the acids by re-precipitation from alkali and recrystallisation from H2O. [Naps & Johns J Am Chem Soc 62 2450 1940, Fredga & Matell Bull Soc Chim Belg 62 47 1953, Wren & Williams J Chem Soc 109 572 1916.] The racemate [635-51-8] has m 166-168o, 168o after recrystallisation from H2O or MeCN. Its S-benzylisothiuronium salt has m 164-165o (from EtOH) [Griediger & Pedersen Acta Chem Scand 9 1425 1955]. [Beilstein 9 IV 3351.]
(R)-(-)-Phenylsuccinic acid Preparation Products And Raw materials

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