ANGIOTENSIN I, HUMAN

CAS No.：484-42-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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ANGIOTENSIN I, HUMAN Basic information

Product Name:	ANGIOTENSIN I, HUMAN
Synonyms:	angiotensin I, Ile(5)-;Angiotensin I (human, rat, mouse);human,mouse,rat;DRVYIHPFHL;HYPERTENSIN I HUMAN;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-OH;H2N-DRVYIHPFHL-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-OH 2CH3COOH 6H2O
CAS:	484-42-4
MF:	C62H89N17O14
MW:	1296.48
EINECS:
Product Categories:	Angiotensin;SignalTransduction
Mol File:	484-42-4.mol

ANGIOTENSIN I, HUMAN Chemical Properties

density	1.43±0.1 g/cm3(Predicted)
storage temp.	-15°C
solubility	≥129.6 mg/mL in DMSO; ≥124.2 mg/mL in H2O; ≥9.16 mg/mL in EtOH
pka	3.27±0.10(Predicted)
form	Powder
color	White
Water Solubility	Soluble to 1 mg/ml in water.

Safety Information

MSDS Information

ANGIOTENSIN I, HUMAN Usage And Synthesis

Uses	Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

ANGIOTENSIN I, HUMAN Preparation Products And Raw materials

Raw materials	Boc-L-Histidine(Tosyl)-->FMOC-L-Arginine-->Boc-Asp(Ochx)-OH-->N-Fmoc-N'-trityl-L-histidine-->N-Boc-L-valine-->FMOC-HIS-OH-->Boc-O-(2-bromo-Cbz)-L-Tyrosine-->BOC-L-Isoleucine-->Fmoc-O-tert-butyl-L-tyrosine-->FMOC-L-Aspartic acid beta-tert-butyl ester-->FMOC-L-Phenylalanine-->FMOC-L-Proline-->FMOC-L-Valine
Preparation Products	L-Leucine, L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-

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