Product

2-Thiohydantoin

CAS No.：503-87-7

Other grades of this product :

2-Thiohydantoin Basic information

Product Name:	2-Thiohydantoin
Synonyms:	2-Thioguidanthion;2-thio-hydantoi;2-thioxo-4-imidazolidinon;2-Thioxo-4-imidazolidinone;2-Thioxo-4-imidazolinone;4-Imidazolidinone,2-thioxo-;Glycine thiohydantoin;Hydantoin, 2-thio-
CAS:	503-87-7
MF:	C3H4N2OS
MW:	116.14
EINECS:	207-977-4
Product Categories:	Building Blocks;Chemical Synthesis;Ring Systems;Building Blocks;Heterocyclic Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
Mol File:	503-87-7.mol

2-Thiohydantoin Chemical Properties

Melting point	229-231 °C (dec.)(lit.)
density	1.346 (estimate)
vapor density	4 (vs air)
refractive index	1.6550 (estimate)
storage temp.	Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Crystalline Powder
pka	8.50±0.10(Predicted)
color	White
CAS DataBase Reference	503-87-7(CAS DataBase Reference)
NIST Chemistry Reference	4-Imidazolidinone, 2-thioxo-(503-87-7)
EPA Substance Registry System	4-Imidazolidinone, 2-thioxo- (503-87-7)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-22
Safety Statements	36
WGK Germany	3
RTECS	MU4200000
TSCA	Yes
HS Code	2934999090

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

2-Thiohydantoin Usage And Synthesis

Chemical Properties	BROWN CRYSTALLINE POWDER
Uses	Reactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
Uses	2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
Uses	Reactant for synthesis of: Drugs with antidiabetic activity Barbituric acid and thiohydantoin derivatives with antimicrobial activity Possible anticancer agents Fibroblast growth factor receptor 1 kinase inhibitors HIV-1 integrase inhibitors Reactant for persilylation

2-Thiohydantoin Preparation Products And Raw materials

Preparation Products

PARABANIC ACID

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