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| GLUTATHIONE S-TRANSFERASE Basic information |
| Product Name: | GLUTATHIONE S-TRANSFERASE | | Synonyms: | RX: GLUTATHIONE R-TRANSFERASE;PURIFIED GST;GultathioneStransferases, ≥25 units/mg protein;glutathione S-transferase from*bovine liver;GLUTATHIONE S-TRANSFERASE FROM*PORCINE L IVER;GLUTATHIONE S-TRANSFERASE FROM RAT*LIVER;GLUTATHIONE S-TRANSFERASE ISOZYME P1-1;GLUTATHIONE S-TRANSFERASE M1-1 ISOZYME | | CAS: | 50812-37-8 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| GLUTATHIONE S-TRANSFERASE Chemical Properties |
| storage temp. | -70°C | | form | lyophilized powder |
| Hazard Codes | B | | WGK Germany | 3 |
| GLUTATHIONE S-TRANSFERASE Usage And Synthesis |
| Uses | Glutathione S-Transferase from human placenta has been used in antigen microarray and informatics analysis. | | General Description | Glutathione S-transferase (GST) is a major detoxification enzyme, and exists as multiple cytoplasmic and membrane-bound isozymes. These isozymes differ in their catalytic activity, as well as in their non-catalytic binding properties. Cytoplasmic isoforms of GST are encoded by five genes, namely α, θ, μ, σ and π. α, μ and π are the most abundant forms in mammals. Membrane bound GST forms are encoded by a single gene. | | Biochem/physiol Actions | Glutathione S-transferase (GST) catalyzes conjugation reactions during phase II metabolism. This enzyme also confers protection against catabolic products of peroxidized lipid and oxidized DNA, and ROS (reactive oxygen species) or electrophiles. | | Purification Methods | It is purified by affinity chromatography using a column prepared by coupling glutathione to epoxy-saturated Sepharose. After washing contaminating proteins, the pure transferase is eluted with buffer containing reduced glutathione. The solution is then concentrated by ultrafiltration, dialysed against phosphate buffer at pH ~7 and stored in the presence of dithiothreitol (2mM) in aliquots at |
| GLUTATHIONE S-TRANSFERASE Preparation Products And Raw materials |
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