Other grades of this product :
| 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information |
| Product Name: | 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT | | Synonyms: | 8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono;8-(4-chlorophenylthio)guanosine-3’,5’-cyclicmonophosphate(8-pcpt-cgmp),sodiumsalt;8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT;8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-PCPT-CGMP NA;8-PCPT-CGMP SODIUM SALT;8-PCPT-CGMP TEA;CGMP, 8-PCPT-, NA | | CAS: | 51239-26-0 | | MF: | C16H14ClN5NaO7PS | | MW: | 509.79 | | EINECS: | | Product Categories: | | Mol File: | 51239-26-0.mol |
| 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: 25 mg/mL | | form | powder | | color | white |
| 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis |
| Uses | 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs). | | Biochem/physiol Actions | Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist. |
| 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials |
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