N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
  • CAS No.:519178-28-0
Other grades of this product :
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Basic information
Product Name:N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
Synonyms:IP6K1 inhibitor TNP (TNP);IP6K Inhibitor - CAS 519178-28-0 - Calbiochem;TNP;N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine;IP3K Inhibitor;IP6K Inhibitor
CAS:519178-28-0
MF:C20H16F3N7O2
MW:443.38
EINECS:247-759-6
Product Categories:
Mol File:519178-28-0.mol
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Chemical Properties
Boiling point 723.4±70.0 °C(Predicted)
density 1.543±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥10mg/mL
pka10.51±0.10(Predicted)
form Yellow solid
color yellow
Safety Information
Hazard Codes T
Risk Statements 25-36
Safety Statements 26-45
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
MSDS Information
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Usage And Synthesis
UsesTNP provides a means of selectively and rapidly modulating cellular InsP7 levels in vivo without affecting levels of other inositol phosphates.
Biochem/physiol ActionsTNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Preparation Products And Raw materials

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