N,N'-bis(salicylideneamino)ethane-manganese(II)

N,N'-bis(salicylideneamino)ethane-manganese(II) structure
  • CAS No.:53177-12-1
Other grades of this product :
N,N'-bis(salicylideneamino)ethane-manganese(II) Basic information
Product Name:N,N'-bis(salicylideneamino)ethane-manganese(II)
Synonyms:N,N'-Bis(salicylidene)-1,2-ethylenediamine-manganese(II) (SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-alphaN)methylidyne]]bis[phenolato-alphaO]](2-)]manganese;(Salen)manganese(III) chloride;(SP-5-13)-Chloro[[2,2′-[1,2-ethanediylbis(nitrilomethylidyne)]bis[phenolato]](2-)-N,N′,O,O′]-manganese;Chloro(bis(salicylidene)ethylenediamine)manganese;Chloro[N,N′-ethylenebis(salicylideneaminato)]manganese;Manganese(salen) chloride;N,N'-bis(salicylideneamino)ethane-manganese(II);EUK-8
CAS:53177-12-1
MF:C16H14ClMnN2O2
MW:356.685609
EINECS:
Product Categories:
Mol File:53177-12-1.mol
N,N'-bis(salicylideneamino)ethane-manganese(II) Chemical Properties
storage temp. -20°C
solubility H2O: soluble1mg/mL, clear
form powder
color , faint to very dark brown
Safety Information
WGK Germany 3
MSDS Information
N,N'-bis(salicylideneamino)ethane-manganese(II) Usage And Synthesis
Uses[N,N 0-Disalicylidene-1,2-ethanediaminato-(2-)]manganese(III) Chloride is an oxidation catalysts and an enzyme mimetic. It also functions as an intermediate in the synthesis of manganese(III) complexes with fluorinated salen derivatives that exhibits antioxidant properties.
Biochem/physiol ActionsEUK-8 is a salen manganese complex that exhibit potent antioxidant activities. EUK-8 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-8 disrupts the pre-formed amyloid fibrils. EUK-8 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils.
N,N'-bis(salicylideneamino)ethane-manganese(II) Preparation Products And Raw materials

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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