4,5-DIMETHOXY-2-NITROBENZYL BROMIDE

4,5-DIMETHOXY-2-NITROBENZYL BROMIDE
  • CAS No.:53413-67-5
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4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Basic information
Product Name:4,5-DIMETHOXY-2-NITROBENZYL BROMIDE
Synonyms:4,5-DIMETHOXY-2-NITROBENZYL BROMIDE;6-NITROVERATRYL BROMIDE;1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene;4,5-Dimethoxy-2-nitrobenzyl bromide 95%;1-(bromomethyl)-2-nitro-4,5-dimethoxybenzene;4,5-dimenoxy-2-nitrobenzyl bromide;3,4-Dimethoxy-6-nitrobenzyl bromide;4,5-Dimethoxy-2-nitro-1-bromomethylbenzene
CAS:53413-67-5
MF:C9H10BrNO4
MW:276.08
EINECS:
Product Categories:
Mol File:53413-67-5.mol
4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Chemical Properties
Melting point 131-133 °C (lit.)
Boiling point 372.3±37.0 °C(Predicted)
density 1.544
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Crystalline Powder or Needles
color Yellow to brown
Sensitive Lachrymatory
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 22-26-27-36/37/39-45
RIDADR UN 3261 8/PG 2
WGK Germany 3
HazardClass 8
PackingGroup III
HS Code 29093090
MSDS Information
ProviderLanguage
SigmaAldrich English
4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Usage And Synthesis
Uses1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene is a useful research chemical.
Uses4,5-Dimethoxy-2-nitrobenzyl bromide (DMNB bromide, 6-nitroveratryl bromide) is suitable reagent used in the synthesis of N-(4,5-dimethoxy-2-nitrobenzyl)vanillylamine which forms caged vanilloid. It may be used in the synthesis of the following:
  • 4-(4′,5′-dimethoxy-2-nitrobenzyloxy)benzaldehyde, a DMNB-caged aldehyde
  • N-[4-[(4,5-dimethoxy-2-nitrobenzyl)oxy]-3-methoxybenzyl]acetamide
  • caged derivative of pyridostatin ([C]-PDS)
  • photosensitive polyimide (PI-DMNB)
  • caged β-ecdysone
  • 4-tert-butyldimethylsilyloxy-1-(2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl)-2-(6-nitroveratrylthio)-1H-benzimidazole, an intermediate in synthesis of phosphoramidite bearing 4-hydroxy-2-mercaptobenzimidazole (SBNV) nucleobase
  • alkylation of dihydrofluorescein
  • 4-(4′,5′-Dimethoxy-2′-nitrobenzyloxy)benzaldehyde
General Description4,5-Dimethoxy-2-nitrobenzyl bromide (DMNBB, 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene) is a 4,5-dimethoxy-2-nitrobenzyl derivative. 4,5-Dimethoxy-2-nitrobenzyl (DMNB) group of DMNBB is used as a photolabile protecting group in caging technology to develop pro-drugs. Synthesis of 1-(bromomethyl)-4,5-dimethoxy-2-nitrobenzene by using 6-nitroveratraldehyde as starting reagent has been reported.
4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Preparation Products And Raw materials
Preparation Products6-Nitroveratraldehyde

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