(R)-(-)-HEXAHYDROMANDELIC ACID

(R)-(-)-HEXAHYDROMANDELIC ACID
  • CAS No.:53585-93-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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(R)-(-)-HEXAHYDROMANDELIC ACID Basic information
Product Name:(R)-(-)-HEXAHYDROMANDELIC ACID
Synonyms:(R)-(-)-HEXAHYDROMANDELIC ACID;R(-)-CYCLOHEXYLHYDROXYACETIC ACID;2-CYCLOHEXYLGLYCOLIC ACID;ALPHA-HYDROXYCYCLOHEXANE-ACETIC ACID;CYCLOHEXYL-HYDROXY-ACETIC ACID;D-HEXAHYDROMANDELIC ACID;Cyclohexylglycolic acid;hexahydromandelic acid
CAS:53585-93-6
MF:C8H14O3
MW:158.2
EINECS:
Product Categories:
Mol File:53585-93-6.mol
(R)-(-)-HEXAHYDROMANDELIC ACID Chemical Properties
Melting point 127-129 °C (lit.)
Boiling point 319.3±15.0 °C(Predicted)
density 1.178±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka3.86±0.11(Predicted)
optical activity[α]18/D 23°, c = 1 in acetic acid
BRN 3196809
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(-)-HEXAHYDROMANDELIC ACID Usage And Synthesis
Uses(R)-(?)-Hexahydromandelic acid can be used:
  • As an intermediate in the synthesis of antimycobacterial compound pyridomycin analogs.
  • As a model α-hydroxy acid compound in the chirality sensing studies of organic probes using circular dichroism technique.
  • As a starting material in the synthesis of chiral ionic liquids, which are applicable as chiral solvents in asymmetric synthesis and as chiral stationary phases in chromatographic separations.
Purification MethodsIt forms hexagonal clusters on recrystallisation from CCl4 or Et2O. [Wood & Comley J Chem Soc 2638 1924, Lettré et al. Chem Ber 69 1594 1936]. The racemate has m 137.2-137.6o (134-135o) [Smith et al. J Am Chem Soc 71 3772 1949]. [Beilstein R-10 II 5; S-10 II 6.]
(R)-(-)-HEXAHYDROMANDELIC ACID Preparation Products And Raw materials

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