Muramyl Dipeptide

Muramyl Dipeptide
  • CAS No.:53678-77-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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Muramyl Dipeptide Basic information
Product Name:Muramyl Dipeptide
Synonyms:acetylmuramyl-alanyl-isoglutamine;n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamin;n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamine;Ac-muramyl-Ala-D-Glu-NH;N-AC-MURAMYL-ALA-D-GLU-NH2;N-AC-MURAMYL-ALA-D-GLU-NH2 2H2O;N-ACETYL-MURAMYL-L-ALA-D-ISOGLN;N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
CAS:53678-77-6
MF:C19H32N4O11
MW:492.48
EINECS:258-696-9
Product Categories:
Mol File:53678-77-6.mol
Muramyl Dipeptide Chemical Properties
alpha D25 +44° (acetic acid)
Boiling point 1071.8±65.0 °C(Predicted)
density 1.390±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: 10 mg/mL, clear, colorless
pka4.44±0.10(Predicted)
form buffered aqueous solution
Merck 13,6329
BRN 4220745
CAS DataBase Reference53678-77-6(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS MA2275260
F 10
MSDS Information
ProviderLanguage
SigmaAldrich English
Muramyl Dipeptide Usage And Synthesis
UsesImmunological adjuvant.
UsesN-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.
Biochem/physiol ActionsMuramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.
Muramyl Dipeptide Preparation Products And Raw materials

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