3-(2-Furyl)acrylic acid

CAS No.：539-47-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

3-(2-Furyl)acrylic acid Basic information

Product Name:	3-(2-Furyl)acrylic acid
Synonyms:	(2E)-3-(2-Furyl)-2-propenoic acid;(2-Furyl)acrylic acid;3-(2-Furanyl)-2-propenoic acid;3-(2-furanyl)-2-propenoicaci;2-PROPENOIC ACID, 3-(2-FURANYL)-;3-(2-FURYL)ACRYLIC ACID;3-(2-furyl)-2-propenoic acid;FURYLACRYLIC ACID
CAS:	539-47-9
MF:	C7H6O3
MW:	138.12
EINECS:	208-718-8
Product Categories:	Building Blocks;C4 to C7;Furan&Benzofuran;Heterocycles;Chemical Synthesis;Heterocyclic Building Blocks;Pharmaceutical Intermediates;Aromatic Cinnamic Acids, Esters and Derivatives;Organic acids;Heterocyclic Compounds;Furans
Mol File:	539-47-9.mol

3-(2-Furyl)acrylic acid Chemical Properties

Melting point	139-141 °C (lit.)
Boiling point	286 °C (lit.)
density	1.2667 (rough estimate)
refractive index	1.4600 (estimate)
Fp	286°C
storage temp.	Store below +30°C.
solubility	Soluble in dichloromethane and diethyl ether.
pka	4.39±0.10(Predicted)
form	Solid
color	Pale Beige
Water Solubility	2g/L(20 ºC)
Merck	14,4297
BRN	81046
Stability:	Light Sensitive
CAS DataBase Reference	539-47-9(CAS DataBase Reference)
NIST Chemistry Reference	2-Propenoic acid, 3-(2-furanyl)-(539-47-9)
EPA Substance Registry System	2-Propenoic acid, 3-(2-furanyl)- (539-47-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25
WGK Germany	3
RTECS	LT8560000
TSCA	Yes
HazardClass	IRRITANT
HS Code	29321900

MSDS Information

Provider	Language
3-(2-Furyl)-2-propenoic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

3-(2-Furyl)acrylic acid Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	3-(2-Furyl)acrylic acid is derivatives used in perfumes.
Uses	3-(2-Furyl)acrylic acid is a reactant used in the preparation of heteroaryl-substituted bis-trifluoromethyl carbinols and trifluoroacetophenone derivatives malonyl-CoA decarboxylase (MCD) inhibitors.
Synthesis Reference(s)	Journal of the American Chemical Society, 78, p. 3425, 1956 DOI: 10.1021/ja01595a044Organic Syntheses, Coll. Vol. 3, p. 426, 1955
Purification Methods	Crystallise the cis-isomer from C6H6 and the trans-isomer from H2O, C6H6 or pet ether (b 80-100o)(charcoal). [Beilstein 18 H 301, 18 III/IV 4143, 18/6 V 306.]

3-(2-Furyl)acrylic acid Preparation Products And Raw materials

Raw materials	Malonic acid-->Acrolein
Preparation Products	3-(5-Nitro-2-furyl)acrylic acid-->4,4-DIFLUOROCYCLOHEXANONE-->D-2-FURYLALANINE-->3-ETHYNYL-2-HYDROXY-PHENOL-->4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE-->ETHYL 3-(2-FURYL)PROPIONATE

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873