L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE

CAS No.：54518-92-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE Basic information

Product Name:	L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE
Synonyms:	H-Leu-CMK.HClL-Leucine chloroMethyl ketone hydr;(S)-3-AMino-1-chloro-5-Methylhexan-2-one hydrochloride;2-Hexanone,3-aMino-1-chloro-5-Methyl-, hydrochloride, (3S)- (9CI);(S)-3-Amino-1-chloro-5-methyl-2-hexanone hydrochloride;Leu-CMK HCl;L-Leu-CMK·HCl;L-leucinechloromethylketoneHCl;H-Leu-Chloromethylketone hydrochloride
CAS:	54518-92-2
MF:	C7H15Cl2NO
MW:	200.11
EINECS:
Product Categories:	Amino Acids;I - Z;Modified Amino Acids
Mol File:	54518-92-2.mol

L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE Chemical Properties

storage temp.

Inert atmosphere,2-8°C

Safety Information

WGK Germany

MSDS Information

Provider	Language
SigmaAldrich	English

L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE Usage And Synthesis

Chemical Properties	White solid
Uses	L-Leucine chloromethyl ketone HCl
Biochem/physiol Actions	L-Leucine chloromethyl ketone (Leu-CMK) is used as a lysosomal cysteine protease inhibitor and as an insulin-like stimulator of lipid synthesis. L-Leucine chloromethyl ketone (Leu-CMK) may be acetylated to generate acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase.

L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE Preparation Products And Raw materials

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