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| JNK INHIBITOR II, NEGATIVE CONTROL Basic information |
| Product Name: | JNK INHIBITOR II, NEGATIVE CONTROL | | Synonyms: | JNK INHIBITOR II, NEGATIVE CONTROL;SAPK INHIBITOR II;N1-METHYL-1,9-PYRAZOLOANTHRONE;N'-METHYL-1,9-PYRAZOLOANTHRONE;SP 600125, negative control;JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem;Dibenz[cd,g]indazol-6(2H)-one, 2-methyl- | | CAS: | 54642-23-8 | | MF: | C15H10N2O | | MW: | 234.25 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| JNK INHIBITOR II, NEGATIVE CONTROL Chemical Properties |
| storage temp. | -20C | | form | Yellow solid |
| JNK INHIBITOR II, NEGATIVE CONTROL Usage And Synthesis |
| Uses | JNK inhibitor II, negative control is the methylated analog of JNK inhibitor II and exhibits a lower affinity for JNK2 and JNK3. This compound is suitable to be used as a negative control in various kinase assays. | | General Description | A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 μM and 24 μM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively). | | Biochem/physiol Actions | Target IC50: 18 μM and 24 μM against JNK2 and JNK3, respectively |
| JNK INHIBITOR II, NEGATIVE CONTROL Preparation Products And Raw materials |
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