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| POLYGUANYLIC ACID (5') POTASSIUM SALT Basic information |
| Product Name: | POLYGUANYLIC ACID (5') POTASSIUM SALT | | Synonyms: | POLY[G] POTASSIUM SALT;POLYGUANYLIC ACID (5') POTASSIUM SALT;POLYGUANYLIC ACID POTASSIUM SALT;polyguanylic acid (5') potassium;Polyguanylic acid potassium salt lyophilized powder | | CAS: | 54684-83-2 | | MF: | C10H14N5O8P | | MW: | 363.22 | | EINECS: | | Product Categories: | | Mol File: | 54684-83-2.mol |
| POLYGUANYLIC ACID (5') POTASSIUM SALT Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder |
| POLYGUANYLIC ACID (5') POTASSIUM SALT Usage And Synthesis |
| Uses | Polyguanylic acid potassium salt has been used:- as a ligand for surface neuropilin-1 (NRP1) for internalization studies
- for intercalation studies with trisubstituted and disubstituted triazole-linked phenyl derivatives CL41, CL42 and CL2r50 using voltammetry method
- as a synthetic polynucleotide for agarose gel electrophoresis analysis
| | General Description | Polyguanylic acid takes up a four-stranded helical structure. It is synthetically produced in Thermus thermophilus from guanosine diphosphate (GDP) and its synthesis is catalyzed by the enzyme polynucleotide phosphorylase. | | Biochem/physiol Actions | Polyguanylic acid acts as a ligand for scavenger receptor and reduces the surface expression neuropilin-1 in endothelial cells. |
| POLYGUANYLIC ACID (5') POTASSIUM SALT Preparation Products And Raw materials |
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