BILIVERDIN DIHYDROCHLORIDE

BILIVERDIN DIHYDROCHLORIDE
  • CAS No.:55482-27-4
Other grades of this product :
BILIVERDIN DIHYDROCHLORIDE Basic information
Product Name:BILIVERDIN DIHYDROCHLORIDE
Synonyms:BILIVERDIN DIHYDROCHLORIDE;BILIVERDIN HYDROCHLORIDE;BiliverdinHCl;Biliverdin hydrochloride (Microbial source);NMGSCKVUURHINJ-DAZZNVSASA-N;3-[(2Z)-2-[[3-(2-carboxyethyl)-5-[(E)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(4-ethenyl-3-methyl-5-oxopyrrol-2-yl)methylidene]-4-methylpyrrol-3-yl]propanoic acid;3-[(2Z,5E)-2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(4-ethenyl-3-methyl-5-oxopyrrol-2-yl)methylidene]-4-methylpyrrol-3-yl]propanoicacid,dihydrochloride
CAS:55482-27-4
MF:C33H35ClN4O6
MW:619.12
EINECS:
Product Categories:Bile Pigments;Porphyrins
Mol File:55482-27-4.mol
BILIVERDIN DIHYDROCHLORIDE Chemical Properties
RTECS DU3033000
storage temp. -20°C
solubility Soluble in DMSO, DMF, and basic aqueous solutions
form Powder
Sensitive Light Sensitive
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
MSDS Information
BILIVERDIN DIHYDROCHLORIDE Usage And Synthesis
UsesBiliverdin dihydrochloride was found responsible for cytoprotection. It was also found to induce tolerance to cardiac allografts. Biliverdin hydrochloride may regulate the cellular heme degradation process by occupying the heme binding site on heme oxygenase which would prevent access of the substrate to the catalytic site of the enzyme.
General DescriptionBiliverdin?(BV) is considered as a near-infrared (NIR)-absorbing pigment, that is endogenic. It is a linear tetrapyrrolic intermediate of heme degradation (heme catabolism) to bilirubin. The bile of amphibia and birds contains only biliverdine, no bilirubin.
Biochem/physiol ActionsBiliverdin (BV) is an excellent anti-inflammatory agent that protects against lipopolysaccharides (LPS)-induced lung injury in mouse endothelial cells. It aids protection in polymicrobial sepsis. Biliverdin has cytoprotective effects on rat livers and protects from prolonged ischemia and reperfusion injury. It also shows antioxidant activities.
BILIVERDIN DIHYDROCHLORIDE Preparation Products And Raw materials

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