Product

(R)-(+)-AMINOGLUTETHIMIDE 97

CAS No.：55511-44-9

Other grades of this product :

(R)-(+)-AMINOGLUTETHIMIDE 97 Basic information

Product Name:	(R)-(+)-AMINOGLUTETHIMIDE 97
Synonyms:	(R)-3-(4-aMinophenyl)-3-ethylpiperidine-2,6-dione;(R)-(+)-Aminoglutethimide 97%;(R)-(+)-AMINOGLUTETHIMIDE 97;(R)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione;CGS-2396;2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3R)-;Aminoglutethimide, D-;(3R)-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione
CAS:	55511-44-9
MF:	C13H16N2O2
MW:	232.28
EINECS:
Product Categories:	Chiral Building Blocks;Cyclic Imides;Organic Building Blocks
Mol File:	55511-44-9.mol

(R)-(+)-AMINOGLUTETHIMIDE 97 Chemical Properties

Melting point	115.5-119.5 °C (lit.)
Boiling point	457.4±45.0 °C(Predicted)
density	1.173±0.06 g/cm3(Predicted)
pka	11.60±0.40(Predicted)
optical activity	[α]20/D +160°, c = 1 in methanol

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

MSDS Information

(R)-(+)-AMINOGLUTETHIMIDE 97 Usage And Synthesis

Uses

(R)-(+)-Aminoglutethimide can be used:

As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.

Definition

ChEBI: The (3R)-enantiomer of aminoglutethimide.

(R)-(+)-AMINOGLUTETHIMIDE 97 Preparation Products And Raw materials

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