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| ANISODAMINE Basic information |
| Product Name: | ANISODAMINE | | Synonyms: | (1r-(1-alpha,3-beta(s*),5-alpha,6-alpha))-.1)oct-3-yleste;Atropine Impurity 5（Atropine EP Impurity E）;(1R,3S,5R,6RS)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate;Hyoscyamine Sulfate Impurity 3（Hyoscyamine Sulfate EP Impurity C）;Atropine impurity E;Hyoscyamine, 6-hydroxy- (6ci, 7ci);aceanisodaMine;Atropine iMpurity E (7-hydroxyhyoscyaMine) | | CAS: | 55869-99-3 | | MF: | C17H23NO4 | | MW: | 305.37 | | EINECS: | | Product Categories: | | Mol File: | 55869-99-3.mol |
| ANISODAMINE Chemical Properties |
| Melting point | 62-63 °C | | Boiling point | 474.6±45.0 °C(Predicted) | | density | 1.27 | | storage temp. | room temp | | solubility | H2O: ≥5mg/mL | | pka | 14.12±0.10(Predicted) | | form | powder | | color | white to beige |
| ANISODAMINE Usage And Synthesis |
| Uses | 6S-Hydroxyhyoscyamine is a derivative of Hyoscyamine (H674300), a natural compound that has inhibitory activity against cholinesterases. | | General Description | Racemic mixture of diastereomers. | | Biochem/physiol Actions | Anisodamine is a non‐specific cholinergic antagonist. It is considered less efficient and less toxic than atropine. Anisodamine interferes with liposome structure and affects cell membrane. It might act as an anti‐oxidant, in protecting against the damage caused by free radicals. Anisodamine is known to reduce cardiac conduction and also prevents arrhythmia. It can block thromboxane synthesis and might possess anti‐thrombotic function. Anisodamine has been useful in a number therapies including septic shock, circulatory disorders, organophosphorus poisoning, opiate addiction, snake bite and radiation damage. Disorders, such as migraine, gastric ulcers, rheumatoid arthritis, gastrointestinal colic, eclampsia, respiratory diseases, acute glomerular nephritis and obstructive jaundice can be treated with the help of anisodamine. |
| ANISODAMINE Preparation Products And Raw materials |
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