Product

4-METHYLPYRAZOLE HYDROCHLORIDE

CAS No.：56010-88-9

Other grades of this product :

4-METHYLPYRAZOLE HYDROCHLORIDE Basic information

Product Name:	4-METHYLPYRAZOLE HYDROCHLORIDE
Synonyms:	FOMEPIZOLE HYDROCHLORIDE;4-METHYLPYRAZOLE HYDROCHLORIDE;Fomepizole/FomepizolechlorideHCl;4-Methyl-1H-pyrazole hydrochloride;4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor
CAS:	56010-88-9
MF:	C4H7ClN2
MW:	118.56
EINECS:
Product Categories:
Mol File:	56010-88-9.mol

4-METHYLPYRAZOLE HYDROCHLORIDE Chemical Properties

Melting point	157-159 °C
storage temp.	2-8°C

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English

4-METHYLPYRAZOLE HYDROCHLORIDE Usage And Synthesis

Uses	4-Methylpyrazole hydrochloride has been used: as a cytochrome P450 2E1 inhibitor as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells
Biochem/physiol Actions	4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.

4-METHYLPYRAZOLE HYDROCHLORIDE Preparation Products And Raw materials

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