2-HYDROXYOLEICACID

2-HYDROXYOLEICACID
  • CAS No.:56472-29-8
Other grades of this product :
2-HYDROXYOLEICACID Basic information
Product Name:2-HYDROXYOLEICACID
Synonyms:2-HYDROXYOLEICACID;2-Hydroxy Oleic Acid (Mixture of Z and E IsoMers);(9Z)-2-Hydroxy-9-octadecenoic Acid;(Z)-2-Hydroxyoctadec-9-enoic acid;cis-2-Hydroxy-9-octadecenoic Acid;Minerval;α-Hydroxyoleic Acid;(9Z)-2-Hydroxy-9-octadecenoic Acid-d17
CAS:56472-29-8
MF:C18H34O3
MW:298.46
EINECS:
Product Categories:Apoptosis;Fatty Acid Derivatives & Lipids;Glycerols;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators
Mol File:56472-29-8.mol
2-HYDROXYOLEICACID Chemical Properties
Melting point 47-50oC
storage temp. room temp
solubility DMSO: >20mg/mL
form Solid
color white to tan
Safety Information
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-39
WGK Germany 3
MSDS Information
2-HYDROXYOLEICACID Usage And Synthesis
Chemical PropertiesOff-White to Pale Beige Solid
UsesAn oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.
Uses2OHOA has been used as:
  • a modulator of the sphingolipid and glycerophospholipid pathway to study its effects on myelination in mice Charcot–Marie–Tooth type 1A (CMT1A) myelinopathy and myelinating dorsal root ganglia cultures
  • in biophysical studies to study its effects on artificial membranes
  • to study its interactions with major membrane lipid films
Biochem/physiol Actions2-Hydroxy oleic acid (2OHOA) is a derivative of oleic acid. It plays a role in membrane organization, alterations in?membrane fluidity, an increase of the tendency to form non-lamellar structures, and remodeling of microdomains by interacting with the lipids in membranes of pathological cells.
2-HYDROXYOLEICACID Preparation Products And Raw materials
Raw materialsOleic acid

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