Other grades of this product :
| HEPARIN MONOSULFATE SODIUM SALT Basic information |
| Product Name: | HEPARIN MONOSULFATE SODIUM SALT | | Synonyms: | Leparan;Sodium heparan sulfate;Sodium heparitin sulfate;suleparoid;N-ACETYLHEPARAN SULFATE BOVINE SODIUM SALT;HEPARITIN SULFATE;HEPARITIN SULFATE SODIUM-POTASSIUM SALT;HEPARITIN SULFATE SODIUM SALT | | CAS: | 57459-72-0 | | MF: | | MW: | 0 | | EINECS: | 232-939-9 | | Product Categories: | | Mol File: | Mol File |
| HEPARIN MONOSULFATE SODIUM SALT Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: 1 mg/mL, clear, colorless |
| HEPARIN MONOSULFATE SODIUM SALT Usage And Synthesis |
| Chemical Properties | Also available fractionated heparan sulfates with lower molecular weights and different Anti-IIa activities. | | Uses | Antithrombotic. | | Uses | Heparan sulfate sodium salt from bovine kidney has been used:- to investigate its effect on proliferation of B cells
- to monitor its role on eye development in E5 embryonic cells
- to study its binding with exosome fibronectin in human trabecular meshwork cells using dot blot
| | Brand name | Orgaran (Organon). | | Biochem/physiol Actions | Heparan sulphate (HS), a ubiquitous glycosaminoglycan, is a polymer of D-glucuronic acid or L-iduronic acid and D-glucosamine (GlcA) sugars. It is synthesized in the cis-Golgi as heparan. In Golgi, final heparan sulphate is synthesized in by the action of enzymes N- and O-HS-sulphotransferases and HS epimerase. The mature HS has 50 to 200 disaccharide units. It is part of the extracellular matrix (ECM) and plays a key role in the oncogenic pathway. Deregulation of heparin sulfate metabolism is implicated in cancer progression. HS is associated with the onset of infectious diseases and inflammatory conditions. HS interaction with Aβ fibrils contributes to the pathophysiology of Alzheimer′s disease. |
| HEPARIN MONOSULFATE SODIUM SALT Preparation Products And Raw materials |
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