DL-TRIHEXYPHENIDYL HYDROCHLORIDE

CAS No.：58947-95-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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DL-TRIHEXYPHENIDYL HYDROCHLORIDE Basic information

Product Name:	DL-TRIHEXYPHENIDYL HYDROCHLORIDE
Synonyms:	DL-Trihexyphenidyl.HCl;a-Cyclohexyl-a-phenyl-1-piperidinepropanol, HCl, Artane;Trihxexyphenidyl Hydrochloride;1-cyclohexyl-1-phenyl-3-piperidin-1-yl-propan-1-ol hydrochloride;1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol hydrochloride;1-cyclohexyl-1-phenyl-3-piperidino-propan-1-ol hydrochloride;α-Cyclohexyl-α-phenyl-1-piperidinepropanol, HCl, Artane;TRIHEXYPHENIDYL HCL
CAS:	58947-95-8
MF:	C20H32ClNO
MW:	337.93
EINECS:	627-735-5
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Antagonists;Cholinergics;Neurotransmitters
Mol File:	58947-95-8.mol

DL-TRIHEXYPHENIDYL HYDROCHLORIDE Chemical Properties

Melting point	258.5°C dec.
storage temp.	Refrigerator
solubility	H₂O: soluble
form	solid
color	white
Stability:	Stable at RT

Safety Information

Hazard Codes	Xn
Risk Statements	22
Safety Statements	36
WGK Germany	3
RTECS	TN2625000

MSDS Information

Provider	Language
SigmaAldrich	English

DL-TRIHEXYPHENIDYL HYDROCHLORIDE Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	DL-Trihexyphenidyl Hydrochloride is an anticholinergic tertiary amine that can gain access to the CNS. It is used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs. The drug is a muscarinic antagonist that qualitatively resembles the belladonna alkaloids in its pharmacological actions and side effects.
Uses	Antiparkinsonian;Anticholinergic
Uses	DL-Trihexyphenidyl hydrochloride has been used to develop a capillary zone electrophoretic method with end-column electrochemiluminescence (ECL)-based detection technique.
Biochem/physiol Actions	DL-trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is known to function as an antimuscarinic agent and a centrally acting anticholinergic. It can be used for controlling the symptoms of all Parkinsonism types, such as the idiopathic, and postencephalitic arteriosclerotic forms. Benzhexol hydrochloride exerts inhibitory functions on the parasympathetic nervous system.

DL-TRIHEXYPHENIDYL HYDROCHLORIDE Preparation Products And Raw materials

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