| 1'-HYDROXYMIDAZOLAM Basic information |
| Product Name: | 1'-HYDROXYMIDAZOLAM |
| Synonyms: | ALPHA-HYDROXYMIDAZOLAM;8-CHLORO-6-(2-FLUOROPHENYL)-1-HYDROXYMETHYL-4H-IMIDAZO[1,5A][1,4]BENZODIAZEPINE;A-HYDROXYMIDAZOLAM;RO 21-6347;1-HYDROXY MIDAZOLAM;1'-HYDROXYMIDAZOLAM;1Hydroxymidazolame;alpha-Hydroxymidazolame |
| CAS: | 59468-90-5 |
| MF: | C18H13ClFN3O |
| MW: | 341.77 |
| EINECS: | 200-659-6 |
| Product Categories: | Aromatics;Heterocycles;Metabolites;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals |
| Mol File: | 59468-90-5.mol |
| 1'-HYDROXYMIDAZOLAM Chemical Properties |
| Melting point | 264-266oC |
| Boiling point | 540.6±60.0 °C(Predicted) |
| density | 1.43±0.1 g/cm3(Predicted) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| pka | 13.59±0.10(Predicted) |
| color | white or off-white |
| Safety Information |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| 1'-HYDROXYMIDAZOLAM Usage And Synthesis |
| Description | 1''-hydroxy Midazolam is the major metabolite of the anesthetic, midazolam. It is produced rapidly by the actions of hepatic cytochrome P450 3A and has been shown to be equipotent to midazolam. |
| Chemical Properties | White Solid |
| Uses | CYP3A4 metabolite of midazolam |
| Uses | A metabolite of Midazolam (M343000). |
| 1'-HYDROXYMIDAZOLAM Preparation Products And Raw materials |
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