TYRAMINE HYDROCHLORIDE

TYRAMINE HYDROCHLORIDE
  • CAS No.:59880-97-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
TYRAMINE HYDROCHLORIDE Basic information
Product Name:TYRAMINE HYDROCHLORIDE
Synonyms:P-(2-AMINOETHYL)PHENOL HYDROCHLORIDE;TIMTEC-BB SBB003808;TYROSAMINE HCL;TYROSAMINE HYDROCHLORIDE;TYRAMINE HCL;TYRAMINE MONOHYDROCHLORIDE;Formyl-Met-Leu-Phe-OH - CAS 59880-97-6 - Calbiochem;2-[[[(2-methoxyphenyl)-oxomethyl]-propylamino]methyl]-4-oxazolecarboxylic acid methyl ester
CAS:59880-97-6
MF:C21H31N3O5S
MW:437.55
EINECS:200-462-5
Product Categories:
Mol File:59880-97-6.mol
TYRAMINE HYDROCHLORIDE Chemical Properties
Melting point 271-274 °C(lit.)
Boiling point 269 °C
density 1.198±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 50 mg/mL, clear, colorless
pka3.50±0.10(Predicted)
form White to off-white lyophilized solid
color White to Almost white
BRN 2315783
CAS DataBase Reference59880-97-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-22
WGK Germany 3
RTECS SJ6050000
F 3-10
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
TYRAMINE HYDROCHLORIDE Usage And Synthesis
UsesInduces leucocyte chemotaxis, and activates macrophages
UsesN-Formyl-Met-Leu-Phe has been used for:
  • creating gradients in Zigmond chamber chemotaxis assay performed on neutrophils
  • use in neutrophil chemotaix assay and
  • determination of the involvement of MAPK-activating protein kinase-2 (MAPKAPK-2) and/or p38, in the signaling pathway of human polymorphonuclear leukocytes (PMNs) stimulated by N-Formyl-Met-Leu-Phe.
DefinitionChEBI: A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor.
General DescriptionN-Formyl-Met-Leu-Phe is a chemotactin peptide, which functions on polymorphonuclear leukocytes (PMN), neutrophils etc.
Biochem/physiol ActionsPotent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
TYRAMINE HYDROCHLORIDE Preparation Products And Raw materials

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