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| TETRAETHYL METHYLENEDIPHOSPHONATE Basic information |
| Product Name: | TETRAETHYL METHYLENEDIPHOSPHONATE | | Synonyms: | methylenedi-phosphonicacitetraethylester;METHYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER;AURORA KA-1506;BIS(DIETHOXYPHOSPHINYL)METHANE;TETRAETHYL(METHYLENE)BISPHOSPHONATE;TETRAETHYL METHYLENEDIPHOSPHONATE;Tetraethyl methylenediphosphonate, 98+%;methanediyl-bis-phosphonic acid tetraethyl ester | | CAS: | 1660-94-2 | | MF: | C9H22O6P2 | | MW: | 288.21 | | EINECS: | 216-764-5 | | Product Categories: | Naphthyridine,Quinoline | | Mol File: | 1660-94-2.mol |
| TETRAETHYL METHYLENEDIPHOSPHONATE Chemical Properties |
| Hazard Codes | Xi,C | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | SZ9150000 | | Hazard Note | Corrosive | | TSCA | Yes | | HS Code | 29319090 |
| TETRAETHYL METHYLENEDIPHOSPHONATE Usage And Synthesis |
| Chemical Properties | clear yellow to yellow-brown liquid | | Uses | Tetraethyl methylidenebisphosphonate, can be used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters as potent anti-inflammatory agents. It is also an intermediate for the synthesis of new bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. | | Uses | Reactant for synthesis of: - Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
- Unnatural alpha-amino acid derivatives containing gem-biphosphonates
- Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption
- Lycopene via Wittig-Horner reaction
- Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase
- Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase
Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition | | Synthesis Reference(s) | Synthetic Communications, 20, p. 1865, 1990 DOI: 10.1080/00397919008053112Tetrahedron Letters, 34, p. 1515, 1993 DOI: 10.1016/S0040-4039(00)60333-7 |
| TETRAETHYL METHYLENEDIPHOSPHONATE Preparation Products And Raw materials |
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