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| bis(3',5')-cyclic diguanylic acid Basic information |
| Product Name: | bis(3',5')-cyclic diguanylic acid | | Synonyms: | bis(3',5')-cyclic diguanylic acid;Cyclic diguanosine monophosphate ( c-diGMP/c-di-GMP ) / cyclic bis ( 3' > 5' ) diguanylic acid;Cyclic di-GMP;c-di-GMP;5GP-5GP;Cyclic-di-GMP，cyclic diguanylate;cyclic diguanylate;3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide | | CAS: | 61093-23-0 | | MF: | C20H24N10O14P2 | | MW: | 690.41 | | EINECS: | | Product Categories: | | Mol File: | 61093-23-0.mol |
| bis(3',5')-cyclic diguanylic acid Chemical Properties |
| Melting point | 193-196 °C (decomp) | | density | 2.70±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | powder | | pka | 0.66±0.70(Predicted) | | color | white to beige |
| bis(3',5')-cyclic diguanylic acid Usage And Synthesis |
| Uses | Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule. | | Definition | ChEBI: A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP. | | Biochem/physiol Actions | Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart. |
| bis(3',5')-cyclic diguanylic acid Preparation Products And Raw materials |
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