3-(2-Methylaminoethyl)indole

3-(2-Methylaminoethyl)indole
  • CAS No.:61-49-4
Other grades of this product :
3-(2-Methylaminoethyl)indole Basic information
Product Name:3-(2-Methylaminoethyl)indole
Synonyms:3-(2-METHYLAMINOETHYL)INDOLE;2-(1H-Indol-3-yl)-N-methylethanamine;3-(2-(methylamino)ethyl)-indol;Dipterine;dl-Methyltryptamine;Indole, 3-(2-(methylamino)ethyl)-;Methyltryptamine;n-methyl-1h-indole-3-ethanamin
CAS:61-49-4
MF:C11H14N2
MW:174.24
EINECS:200-507-9
Product Categories:Tryptamines;Building Blocks;C11;Chemical Synthesis;Heterocyclic Building Blocks;Indoles;Heterocyclic Compounds
Mol File:61-49-4.mol
3-(2-Methylaminoethyl)indole Chemical Properties
Melting point 87-89 °C(lit.)
Boiling point 295.23°C (rough estimate)
density 0.9649 (rough estimate)
refractive index 1.6210 (estimate)
storage temp. -20°C
pka17.26±0.30(Predicted)
form Shiny Crystalline Powder or Flakes
color White to off-white
CAS DataBase Reference61-49-4(CAS DataBase Reference)
NIST Chemistry Reference1H-Indole-3-ethanamine, N-methyl-(61-49-4)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS NM0450000
HS Code 29339980
MSDS Information
ProviderLanguage
3-(2-Methylaminoethyl)indole English
SigmaAldrich English
ACROS English
3-(2-Methylaminoethyl)indole Usage And Synthesis
Chemical Propertieswhite to off-white shiny cryst. powder or flakes
UsesReactant for preparation of:• ;Manzamine analogues for the control of neuroinflammation and cerebral infections1• ;Serotonin 4 receptors (5-HT4) receptor agonists2• ;A sulful-containing indole alkaloid, glypetelotine3• ;Selective inhibitors of cyclin dependent kinase (CDK4)4• ;Antagonist of the human tachykinin NK-2 receptor5• ;Inhibitors of the tyrosine-specific protein kinase pp60c-src SH2 Domain6
UsesN-Methyltryptamine (NMT) is a naturally-occurring tryptamine which may be derived from L-tryptophan or, indirectly, from serotonin. While substituted NMTs are psychoactive through their effects on monoamine action, NMT appears to be rapidly metabolized by monoamine oxidases. This product is intended for research and forensic applications.[Cayman Chemical]
UsesN-Methyltryptamine is an alkylamine, a putative hallucinogen constituent from the root of Mimosa ophthalmocentra. An alkaloid from the leaves of Hammada scoparia.
Synthesis Reference(s)Chemical and Pharmaceutical Bulletin, 49, p. 87, 2001Journal of Medicinal Chemistry, 19, p. 99, 1976 DOI: 10.1021/jm00223a016
3-(2-Methylaminoethyl)indole Preparation Products And Raw materials
Preparation ProductsN-METHYL-N-ISOPROPYLTRYPTAMINE(MIPT)

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