1-METHYL-2-INDOLINONE

1-METHYL-2-INDOLINONE
  • CAS No.:61-70-1
Other grades of this product :
1-METHYL-2-INDOLINONE Basic information
Product Name:1-METHYL-2-INDOLINONE
Synonyms:2,3-DIHYDRO-1-METHYLINDOL-2-ONE;1-METHYLOXINDOLE;1-METHYL-2-INDOLINONE;1-METHYL-1,3-DIHYDRO-2H-INDOL-2-ONE;TIMTEC-BB SBB006878;N-METHYLOXINDOLE;N-METHYL-2-OXINDOLE;1,3-dihydro-1-methyl-2h-indol-2-on
CAS:61-70-1
MF:C9H9NO
MW:147.17
EINECS:612-193-4
Product Categories:Chemical intermediate for Lercanidipine and Benidipine;Organic acids;(intermediate of lercanidine);Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:61-70-1.mol
1-METHYL-2-INDOLINONE Chemical Properties
Melting point 85-88 °C(lit.)
Boiling point 110-120 °C(Press: 1 Torr)
density 1.167±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka0.40±0.20(Predicted)
CAS DataBase Reference61-70-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS NM2208800
HS Code 2933790090
MSDS Information
1-METHYL-2-INDOLINONE Usage And Synthesis
Chemical PropertiesLight-Yellow Solid
Uses1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents.
UsesReactant for preparation of:
  • Fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching
  • Irreversible Nek2 Kinase Inhibitors
  • Anticancer agents
  • Antimalarial agents
  • Antitimor agents
  • Germination stimulants in plants
  • Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)
  • Retinoic acid analogs
  • Potential anti-multiple sclerosis agents
  • Inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase
Uses1-Methyl-2-oxindole is used in the prevention and therapy of atherosclerotic degradation of arterial walls.
Synthesis Reference(s)Journal of the American Chemical Society, 107, p. 435, 1985 DOI: 10.1021/ja00288a027Journal of Heterocyclic Chemistry, 23, p. 1163, 1986 DOI: 10.1002/jhet.5570230439

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