TRANS-4-NITROCINNAMOYL CHLORIDE

CAS No.：61921-33-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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TRANS-4-NITROCINNAMOYL CHLORIDE Basic information

Product Name:	TRANS-4-NITROCINNAMOYL CHLORIDE
Synonyms:	(2E)-3-(4-nitrophenyl)acryloyl chloride;2-propenoyl chloride, 3-(4-nitrophenyl)-, (2E)-;TRANS-4-NITROCINNAMOYL CHLORIDE;(E)-3-(4-nitrophenyl)acryloyl chloride;trans-4-Nitrocinnamoyl chloride 97%;3-(4-nitrophenyl)acryloyl chloride
CAS:	61921-33-3
MF:	C9H6ClNO3
MW:	211.6
EINECS:
Product Categories:	Acid Halides;Carbonyl Compounds;Organic Building Blocks
Mol File:	61921-33-3.mol

TRANS-4-NITROCINNAMOYL CHLORIDE Chemical Properties

Melting point	150-153 °C(lit.)
Boiling point	319.6±17.0 °C(Predicted)
density	1.403±0.06 g/cm3(Predicted)

Safety Information

Hazard Codes	C
Risk Statements	34
Safety Statements	26-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
HazardClass	8
PackingGroup	III

MSDS Information

Provider	Language
SigmaAldrich	English

TRANS-4-NITROCINNAMOYL CHLORIDE Usage And Synthesis

Uses

trans-4-Nitrocinnamoyl chloride may be used as derivatization reagent for the analysis of perhexiline and its monohydroxy metabolite in plasma by HPLC. It may be used as derivatization reagent to investigate the in vitro enzyme kinetics and CYP isoform selectivity of perhexiline monohydroxylation using human liver microsomes.

TRANS-4-NITROCINNAMOYL CHLORIDE Preparation Products And Raw materials

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