ALPHA-METHYL-GAMMA-BUTYROLACTONE

CAS No.：1679-47-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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ALPHA-METHYL-GAMMA-BUTYROLACTONE Basic information

Product Name:	ALPHA-METHYL-GAMMA-BUTYROLACTONE
Synonyms:	4-Hydroxy-2-methylbutanoic acid lactone;4-Hydroxy-2-methylbutyric acid lactone;alpha-Methylbutyrolactone;Methyl-.gamma.butyrolactone,.alpha.-methyl-.gamma.-butyrolactone,butyricacid,4-hydroxy-2-methyl-,.gamma.-lactone;(±)-3-Methyl-dihydro-furan-2-one;(R,S)-3-Methyl-dihydro-furan-2-one;2(3H)-Furanone,dihydro-3-methyl-;2-Methyl-4-butanolide
CAS:	1679-47-6
MF:	C5H8O2
MW:	100.12
EINECS:	216-846-0
Product Categories:
Mol File:	1679-47-6.mol

ALPHA-METHYL-GAMMA-BUTYROLACTONE Chemical Properties

Boiling point	78-81 °C/10 mmHg (lit.)
density	1,06 g/cm³
refractive index	n20/D 1.432(lit.)
Fp	163 °F
storage temp.	2-8°C
solubility	THF: soluble
form	clear liquid
color	Colorless to Almost colorless
BRN	80418
CAS DataBase Reference	1679-47-6

Safety Information

Safety Statements	23-24/25
WGK Germany	3
HS Code	2932209090

MSDS Information

Provider	Language
SigmaAldrich	English

ALPHA-METHYL-GAMMA-BUTYROLACTONE Usage And Synthesis

Uses	ALPHA-METHYL-GAMMA-BUTYROLACTONE was used as model compound in Bracketing experiments to investigate the thermodynamically favored site of reaction of pilocarpine.
Uses	α-Methyl-γ-butyrolactone was used as model compound in Bracketing experiments to investigate the thermodynamically favored site of reaction of pilocarpine.
General Description	α-Methyl-γ-butyrolactone undergoes benzylation to give racemic α-benzyl-α-methyl-γ-butyrolactone.

ALPHA-METHYL-GAMMA-BUTYROLACTONE Preparation Products And Raw materials

Preparation Products

3-Methyl-2-oxo-tetrahydro-furan-3-carbaldehyde-->3-methyl-4,5-dihydrofuran-->3-METHYL-2(5H)-FURANONE-->3-METHYLTETRAHYDROFURAN-->1,4-PENTANEDIOL-->TETRAHYDRO-3-FUROIC ACID

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