Product

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

CAS No.：64118-84-9

Other grades of this product :

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Basic information

Product Name:	2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonyms:	(o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci;(o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid;DICLOFENAC, 4'-HYDROXY-;4'-OHD;4-OHD;4-HYDROXY DICLOFENAC;4'-HYDROXYDICLOFENAC;2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
CAS:	64118-84-9
MF:	C14H11Cl2NO3
MW:	312.15
EINECS:	626-698-2
Product Categories:	Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	64118-84-9.mol

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties

Melting point	178-185°C dec.
Boiling point	432.7±45.0 °C(Predicted)
density	1.520±0.06 g/cm3(Predicted)
Fp	2℃
storage temp.	-20°C
solubility	Soluble in DMSO, ethanol or methanol
form	neat
pka	4.17±0.10(Predicted)
BRN	4198042

Safety Information

Hazard Codes	T,N,Xn,F
Risk Statements	25-37/38-41-50/53-36-20/21/22-11
Safety Statements	26-39-45-60-61-36/37-16
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	AG6542800
HazardClass	6.1

MSDS Information

Provider	Language
SigmaAldrich	English

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Usage And Synthesis

Description	4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE₂ synthesis, it demonstrates anti-inflammatory and analgesic properties.
Chemical Properties	Light Violet Solid
Uses	A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.
Uses	A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor
Uses	A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac
Definition	ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.
General Description	4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials

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