MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
  • CAS No.:65144-34-5
Other grades of this product :
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Basic information
Product Name:MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
Synonyms:N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE;methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone;N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE;MEOSUC-APPV-CMK;MEOSUC-AAPV-CMK;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;MEOSUC-ALA-ALA-PRO-VAL-CMK;ELASTASE INHIBITOR III
CAS:65144-34-5
MF:C22H35ClN4O7
MW:502.99
EINECS:
Product Categories:ProteaseInhibitors
Mol File:65144-34-5.mol
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties
Melting point 159-161 °C
Boiling point 809.4±65.0 °C(Predicted)
density 1.234±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility ethanol: 50 mg/mL, clear, colorless
pka13.05±0.20(Predicted)
form Solid
Sensitive Moisture Sensitive
BRN 6167019
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10
MSDS Information
ProviderLanguage
SigmaAldrich English
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Usage And Synthesis
UsesA potent irreversible inhibitor of human leukocyte elastase
DefinitionChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.
General DescriptionN-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.
Biochem/physiol ActionsN-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials

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