AC-DEVD-CHO

CAS No.：169332-60-9

Other grades of this product :

AC-DEVD-CHO Basic information

Product Name:	AC-DEVD-CHO
Synonyms:	Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%;AC-DEVD-CHO?, >98%;Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem;N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE;N-AC-ASP-GLU-VAL-ASP-CHO;N-ACETYL-ASP-GLU-VAL-ASP-AL;N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE);CPP32/APOPAIN INHIBITOR
CAS:	169332-60-9
MF:	C20H30N4O11
MW:	502.47
EINECS:
Product Categories:	peptides;Caspase 10;Caspase 3;Caspase 7;Caspase 8;Caspase Inhibitors;Caspase Inhibitors and Substrates;Peptides and Proteins;Peptides for Cell Biology;Protease Inhibitor Specificity Index;Protease Inhibitors;A to C;A-AM;Aldehydes;and Substrates;Apoptosis and Cell Cycle;Apoptosis Enzymes;Application Index;Bioactive Small Molecules;Biochemicals and Reagents;Building Blocks;C13-C60;Carbonyl Compounds;Caspases;Cell Biology;Cell Signaling and Neuroscience;Cell Signaling Enzymes;Chemical Synthesis;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme;Enzymes;Inhibitors;Organic Building Blocks;Pepetides
Mol File:	169332-60-9.mol

AC-DEVD-CHO Chemical Properties

Boiling point	1021.1±65.0 °C(Predicted)
density	1.374±0.06 g/cm3(Predicted)
RTECS	EK7643000
storage temp.	-20°C
solubility	H₂O: 1 mg/mL
form	powder
pka	4.19±0.10(Predicted)
color	white
Sensitive	Moisture Sensitive

Safety Information

WGK Germany

MSDS Information

Provider	Language
SigmaAldrich	English

AC-DEVD-CHO Usage And Synthesis

Uses	Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase
Uses	N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
Definition	ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.
General Description	N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.
Biochem/physiol Actions	N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.

AC-DEVD-CHO Preparation Products And Raw materials

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